In 15th-century Venice it is a dangerous time to be alive. Bodies keep washing up on the banks of the city. These bodies are especially hard to identify, since they have been skinned. In the present day, a famous portrait by Titian has been discovered. Its subject: the 15th-century suspected murderer Angelico Vespucci. The skins of Vespucci's victims were never found, so his guilt was never proven. Although it is rumoured that when the portrait arises, so will the man. And when flayed bodies start turning up all over the world, it looks like this is more than just a superstition.